Average customer rating:
|
Throw Away Your Resume (Throw Away Your Resume!)
Robert M. Hochheiser
Manufacturer: Barrons Educational Series Inc
ProductGroup: Book
Binding: Paperback
General
| Job Hunting & Careers
| Business & Investing
| Subjects
| Books
Job Hunting
| Job Hunting & Careers
| Business & Investing
| Subjects
| Books
Resumes
| Job Hunting & Careers
| Business & Investing
| Subjects
| Books
General
| Business & Investing
| Subjects
| Books
Management & Leadership
| Business & Investing
| Subjects
| Books
| Business Ethics
| Consolidation & Merger
| Decision-Making & Problem Solving
| Distribution & Warehouse Management
| Industrial
| Information Management
| Leadership
| Management
| Management Science
| Motivational
| Negotiating
| Operations Research
| Planning & Forecasting
| Pricing
| Production & Operations
| Project Management
| Quality Control
| Risk Assessment
| Statistics
| Strategy & Competition
| Systems & Planning
| Systems Analysis
| Teams
| Total Quality Management
| Training
ASIN: 0812093348 |
Average customer rating:
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Throw Away Your Resume
Robert Hochheiser
Manufacturer: Barron's Educational Series, Inc.
ProductGroup: Book
Binding: Paperback
ASIN: B000OMN8KI |
Product Description
A career placement strategy that shows how to take full control of your job search and get the position you really want.
Average customer rating:
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Throw Away Your Resume and Get That Job
Warren J. Rosaluk
Manufacturer: Prentice Hall Trade
ProductGroup: Book
Binding: Hardcover
General
| Business & Investing
| Subjects
| Books
Management & Leadership
| Business & Investing
| Subjects
| Books
| Business Ethics
| Consolidation & Merger
| Decision-Making & Problem Solving
| Distribution & Warehouse Management
| Industrial
| Information Management
| Leadership
| Management
| Management Science
| Motivational
| Negotiating
| Operations Research
| Planning & Forecasting
| Pricing
| Production & Operations
| Project Management
| Quality Control
| Risk Assessment
| Statistics
| Strategy & Competition
| Systems & Planning
| Systems Analysis
| Teams
| Total Quality Management
| Training
ASIN: 0139205950 |
Customer Reviews:
Good, but confused.......2003-04-23
For those who are stuck between jobs, or who are contemplating a change, this book makes a fine companion to "Ask the Headhunter" by Nick Corcodilos.
The title says it all: if you're looking for a job and you line up with the herd, you will lose. Become a salesman (of yourself) and win.
I used some of the techniques in this book to land my last job and I can attest to how well they work. The book is also very easy to read, as all of the concepts are chopped up into small bite-sized chunks, the writing is natural, and the subject matter is not difficult.
Unfortunately about half-way through, Rosaluk forgets his topic and starts writing about these useless tips on how to reformat your resume, how to make it better, etc. (That's why he only gets 3 stars)
Keep reading the title; that is the key. It works.
Average customer rating:
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Throw Away Your Resume and Get That Job
Manufacturer: Prentice Hall
ProductGroup: Book
Binding: Hardcover
ASIN: 013920587X |
Average customer rating:
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Throw Away Your Resume and Get That Job
Warren J. Rosaluk
Manufacturer: Prentice Hall Trade
ProductGroup: Book
Binding: Paperback
ASIN: B000OIWYCA |
Average customer rating:
|
Doing Good for the Aged: Volunteers in an Ombudsman Program
Pat M. Keith
Manufacturer: Praeger Publishers
ProductGroup: Book
Binding: Hardcover
Volunteer Work
| Job Hunting & Careers
| Business & Investing
| Subjects
| Books
Social Services & Welfare
| Poverty
| Current Events
| Nonfiction
| Subjects
| Books
General
| Social Sciences
| Nonfiction
| Subjects
| Books
Gerontology
| Social Sciences
| Nonfiction
| Subjects
| Books
Social Work
| Social Sciences
| Nonfiction
| Subjects
| Books
General
| Sociology
| Social Sciences
| Nonfiction
| Subjects
| Books
History
| Sociology
| Social Sciences
| Nonfiction
| Subjects
| Books
All Amazon Upgrade
| Amazon Upgrade
| Stores
| Books
Business & Investing
| Amazon Upgrade
| Stores
| Books
Nonfiction
| Amazon Upgrade
| Stores
| Books
ASIN: 027597698X |
Book Description
Despite an increased emphasis on independent and assisted living for older persons, the need for oversight of care, welfare, and rights of the aged in nursing facilities remains. Indeed, in recognition of the need to provide advocacy services for vulnerable elderly, the Older Americans Act was amended in 1978 to require states to establish nursing home ombudsman/advocacy programs. Ombudsman programs are based on the assumption that community involvement through volunteers will have a "watchdog" effect on behalf of residents and increase accountability among staff and administrators of nursing homes. The present study reveals volunteers' experiences in ombudsman programs. It provides insight into volunteers' thoughts about their work and their capabilities prior to their involvement as well as independent measures of the work of volunteers.
Average customer rating:
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Unemployment, Public Policy and the Changing Labour Market
Manufacturer: Policy Studies Institute
ProductGroup: Book
Binding: Paperback
General
| Popular Economics
| Business & Investing
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| Books
Labor & Industrial Relations
| Economics
| Business & Investing
| Subjects
| Books
Unemployment
| Economics
| Business & Investing
| Subjects
| Books
General
| Business & Investing
| Subjects
| Books
Labor & Industrial Relations
| Politics
| Nonfiction
| Subjects
| Books
Public Policy
| Political Science
| Social Sciences
| Nonfiction
| Subjects
| Books
Federal Government
| Levels of Government
| Political Science
| Social Sciences
| Nonfiction
| Subjects
| Books
ASIN: 0853746397 |
Average customer rating:
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Health, Healing and the Amuse System: Humor As Survival Training
Paul E. McGhee
Manufacturer: Kendall/Hunt Publishing Company
ProductGroup: Book
Binding: Paperback
General
| Humor
| Entertainment
| Subjects
| Books
Self-Help & Psychology
| Humor
| Entertainment
| Subjects
| Books
Theories of Humor
| Humor
| Entertainment
| Subjects
| Books
Stress Management
| Self-Help
| Health, Mind & Body
| Subjects
| Books
Applied Psychology
| Psychology & Counseling
| Health, Mind & Body
| Subjects
| Books
Humor
| Stress
| Personal Health
| Health, Mind & Body
| Subjects
| Books
Similar Items:
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The Healing Power of Humor
-
Laffirmations
-
Anatomy of an Illness as Perceived by the Patient
-
Awaken the Giant Within : How to Take Immediate Control of Your Mental, Emotional, Physical and Financial Destiny!
ASIN: 0787228478 |
Average customer rating:
- Musicians bible
- A realistic book for any musician who is turning their hobby into a career.
- Nothing new...
- IF YOU ARE A WORKING MUSICIAN, HERE'S SOME GREAT IDEAS
|
The Business of Getting More Gigs as a Professional Musician
Bob Popyk
Manufacturer: Hal Leonard
ProductGroup: Book
Binding: Paperback
General
| Reference
| Music
| Entertainment
| Subjects
| Books
Business
| Music
| Entertainment
| Subjects
| Books
General
| Music
| Entertainment
| Subjects
| Books
General
| Theater
| Performing Arts
| Arts & Photography
| Subjects
| Books
General
| Performing Arts
| Arts & Photography
| Subjects
| Books
General
| Arts & Photography
| Subjects
| Books
Look Inside Entertainment Books
| Trip
| Specialty Stores
| Books
Similar Items:
-
The Gigging Musician: How to Get, Play, and Keep the Gig
-
Gigging: A Practical Guide for Musicians
-
Getting Gigs: The Musicians & Singers Survival Guide to Booking Better Paying Jobs
-
Moneymaking Music
-
Making Money Making Music: The Musician's Guide to Cover Gigs
ASIN: 0634058428 |
Book Description
Getting more gigs doesn't just happen. Musicians have to make it happen. Despite a myriad of convenient excuses to choose from - the economy is off, money is tight, unemployment is high, not as many clubs are hiring, budget cuts mean fewer corporate gigs - there are always some musicians who do exceptionally well and work constantly, regardless of the month, year, season, economy or their location. A collection of Bob Popyk's most talked-about columns from International Musician magazine, The Business of Getting More Gigs as a Professional Musician will clue you in to what the musicians mentioned above already know and do. Covering in detail topics such as attitude, gig etiquette, business basics, money and diversifying, Popyk gives practical pointers to help you have a plan, network effectively, promote your assets, and market yourself constantly. He points out the need to treat gig-seeking like a business, and take it just as seriously. Musicians who take his advice will soon be well on their way to more and better-paying gigs. Also available by Bob Popyk: How to Find Gigs That Pay Big Bucks 00320370 DVD $19.95
Customer Reviews:
Musicians bible.......2007-01-10
This book is an excellent resource. It gives very useful suggestions on generating work, in fact I have put several of Bob's ideas into place. I have booked a venue, musicians and done publicity after being inspired by this book.
i recommend this book to all musicians who aspire to be professional-who would like to give up their day job.
A realistic book for any musician who is turning their hobby into a career........2006-04-07
Too many musicians expect work to simply come to them. Making a living as a musician isn't easy, and this book comes up with ideas for bringing in more bucks. There is no "one idea" here that will help make a fortune. Unfortunately you have to work at it. There seems to be less and less work for musicians today. At least this book addresses that fact and comes up with some thoughts on how to bring in the work that still might be out there.
Nothing new... .......2006-03-24
If you are new to the business of getting gigs, and know absolutely nothing about business in general, then this book may be helpful. I was looking for something more.
To me it seemed that the author's approach was that he was speaking to dead beat musicians who are lazy and complaining all the time. I personally think that there are many talented and hard working musicians out there who hustle each and every day to get gigs and are far beyond needing the advice that you must pick up the phone, treat your band like a business, etc. We already know all of this.
I was looking for a book (and still am) that would get into more depth on this subject of getting gigs and give some original ideas. This book had nothing new to offer me.
However, if you are brand new to the business, and to the business world in general, you may get something from it.
IF YOU ARE A WORKING MUSICIAN, HERE'S SOME GREAT IDEAS.......2003-08-31
I have read Mr. Popyk's columns in the International Musician as well as The Music Trades magazine. It's nice to see the best ideas for getting more work all together in one book. There are so many things musicians can do to keep their calendar full if we actually treat it like a business. I've been playing casual dates for years and still like to be reminded of things I could be doing to get more gigs. A lot of the chapters have me thinking "I can do that", or "Why didn't I think of that?". Do yourself a favor if you are looking for gigs...read this book! (Unless that is, you have all the work you can handle)
Average customer rating:
- Excellent Read
- Startlingly Good!
- Very Insightful!
- Don't bother.
- Enjoyable and provacative!
|
Golden State, Golden Youth: The California Image in Popular Culture, 1955-1966
Kirse Granat May
Manufacturer: The University of North Carolina Press
ProductGroup: Book
Binding: Paperback
Popular Culture
| Social Sciences
| Nonfiction
| Subjects
| Books
General
| Social Sciences
| Nonfiction
| Subjects
| Books
General
| Sociology
| Social Sciences
| Nonfiction
| Subjects
| Books
Culture
| Sociology
| Social Sciences
| Nonfiction
| Subjects
| Books
Media Studies
| Social Sciences
| Nonfiction
| Subjects
| Books
General
| State & Local
| United States
| Americas
| History
| Subjects
| Books
California
| State & Local
| United States
| Americas
| History
| Subjects
| Books
General
| Arts & Photography
| Subjects
| Books
Look Inside Entertainment Books
| Trip
| Specialty Stores
| Books
All Titles
| Qualifying Textbooks - Fall 2007
| Stores
| Books
Arts & Photography
| Qualifying Textbooks - Fall 2007
| Stores
| Books
Nonfiction
| Qualifying Textbooks - Fall 2007
| Stores
| Books
Similar Items:
-
Our Town: Race, Housing and the Soul of Suburbia
-
Crabgrass Frontier: The Suburbanization of the United States
-
Less Than Zero
-
Suburban Nation: The Rise of Sprawl and the Decline of the American Dream
-
Revolutionary Road
ASIN: 0807853623
Release Date: 2001-12-04 |
Book Description
Seen as a land of sunshine and opportunity, the Golden State was a mecca for the post-World War II generation, and dreams of the California good life came to dominate the imagination of many Americans in the 1950s and 1960s. Nowhere was this more evident than in the explosion of California youth images in popular culture. Disneyland, television shows such as The Mickey Mouse Club, Gidget and other beach movies, the music of the Beach Boys--all these broadcast nationwide a lifestyle of carefree, wholesome fun supposedly enjoyed by white, middle-class, suburban young people in California.
Tracing the rise of the California teen as a national icon, Kirse May shows how idealized images of a suburban youth culture soothed the nation's postwar nerves while denying racial and urban realities. Unsettling challenges to this mass-mediated picture began to arise in the mid-1960s, however, with the Free Speech Movement's campus revolt in Berkeley and race riots in Watts. In his 1966 campaign for the governorship of California, Ronald Reagan transformed the backlash against the "dangerous" youths who fueled these actions into political triumph. As May notes, Reagan's victory presaged a rising conservatism across the nation.
Customer Reviews:
Excellent Read.......2002-08-23
Interesting and extremely readable, this book made me realize how much I had bought into the California myth as I was growing up in the 60's, as well as allowing me some enjoyable trips down memory lane. The author's writing style allowed me to see the cause and effects of California pop culture of the 50's and 60's from a much wider frame of reference; educating me without drowning me in pompous academic babbling.
I heartily recommend this book!
Startlingly Good!.......2002-08-16
I heard an interview with the Author on NPR. Being a former mouseketeer and a closet fan of the Frankie and Annette beach films, I thought the book would be right-up my alley. May puts together a remarkably entertaining and enlightening piece of work. By analyzing this period in American history through the skewed lens of popular culture, May shows how many of those living in the 50's and 60's believed (including some of California's elected officials) that California had some kind of magical immunity to the societal and racial problems that affected the rest of the country at the time. She also illustrates how deeply the nation was shocked when reality caught-up with the illusion. While depicting the Popular Culture images packaged and shipped from sunny California, May doesn't take an overly moralistic tone. Also, the writing is refreshingly free of bloated academic gibberish. It is clear May sifted through volumes of research and has produced a tight and compelling book. I give Golden State, Golden Youth my strongest recommendation, especially to those ever to have listened to a Beach Boys record, watched Frankie and Annette, or donned a pair of mouse ears.
Very Insightful!.......2002-07-18
A friend referred this book to me and although I'm not normally into this kind of book I found it very interesting. May's thoughts on Disney and the surf generation were very eye opening and it made me look at today's pop culture in a whole new way. Good reading, great ideas.
Don't bother........2002-07-15
For those who have never lived in, been to, or heard of California, or indeed have never reflected momentarily on the relation between media images and public opinion, this book might offer something like fresh insights; for everyone else, this warmed-over dissertation is little more than a neat summary of cliches, inaccuracies, and other's ideas. The scholarship is alternately myopic, specious, and unoriginal (though occasionally it is all three at once!) and the writing itself either cringe-worthy or just plain bland (it reads much like the plagiarized book report of an accomplished high school student). There are a few sites out there already which document the absurdities of this book better than I could here, so I won't waste my/your time. I'm not sure what I can say in defense of the book or those who have endorsed it above (one of whom I suspect of being a relative); but to the latter I can offer a suggestion: check out either Mike Davis or Kevin Starr to see how derivative this book is (also see Steven Gaines and Timothy White's respective books on the Beach Boys). And to the prospective buyer: don't bother with this hackneyed term paper, buy _City of Quartz_ and listen to "Pet Sounds" instead!
Enjoyable and provacative!.......2002-06-26
What a fun book to read. I would highly recommend anyone this text. It really keeps you thinking, but she is such a good writer, she engages your brain but never overwhelms. Fennis Dembo!
I brought this home on Friday, and had it polished off by Sunday afternoon. My wife got tired of me reading passages out loud to her, so she made me shut up until she had a chance to read it.
Average customer rating:
|
Sit & Solve Commuter Anagram Puzzles (Sit & Solve Series)
Darren Rigby
Manufacturer: Sterling
ProductGroup: Book
Binding: Paperback
General
| Puzzles & Games
| Entertainment
| Subjects
| Books
Puzzles
| Puzzles & Games
| Entertainment
| Subjects
| Books
General
| Puzzles & Games
| Entertainment
| 4-for-3 Books Store
| Stores
| Books
Puzzles
| Puzzles & Games
| Entertainment
| 4-for-3 Books Store
| Stores
| Books
All 4-for-3 Deals
| 4-for-3 Books Store
| Stores
| Books
Similar Items:
-
Sit & Solve Commuter Cryptograms (Sit & Solve Series)
-
Palindromes and Anagrams
ASIN: 1402725426 |
Book Description
The blockbuster Sit & Solve series spins off to the delight of puzzle lovers on the go. Just like the originals, these portable collections feature the highest-quality brainteasers compiled by the top creators--such as Matt Gaffney, the author of dozens of puzzle books. And with these eye-catching shapes--including a coffee cup, subway, bus, and bagel--a trip to the office will never be the same.
Average customer rating:
|
Sit and Solve Commuter Anagram Puzzles
Manufacturer: STERLING
ProductGroup: Book
Binding: Paperback
ASIN: B000GTHV34 |
Average customer rating:
- Tries Hard to Cover Everything
|
Developing eBay Business Tools For Dummies (For Dummies (Business & Personal Finance))
John Kaufeld , and
Tim Harvey
Manufacturer: For Dummies
ProductGroup: Book
Binding: Paperback
General
| Business & Investing
| Subjects
| Books
Retailing
| Industries & Professions
| Business & Investing
| Subjects
| Books
General
| E-commerce
| Industries & Professions
| Business & Investing
| Subjects
| Books
Software Development
| Software Design, Testing & Engineering
| Programming
| Computers & Internet
| Subjects
| Books
General
| Programming
| Computers & Internet
| Subjects
| Books
General
| Computers & Internet
| Subjects
| Books
eBay
| Business & Culture
| Computers & Internet
| Subjects
| Books
E-Commerce
| Business & Culture
| Computers & Internet
| Subjects
| Books
General
| Software
| Computers & Internet
| Subjects
| Books
Look Inside Business Books
| Trip
| Specialty Stores
| Books
Look Inside Computer Books
| Trip
| Specialty Stores
| Books
All Amazon Upgrade
| Amazon Upgrade
| Stores
| Books
Business & Investing
| Amazon Upgrade
| Stores
| Books
Computers & Internet
| Amazon Upgrade
| Stores
| Books
For Dummies
| Amazon Upgrade
| Stores
| Books
Similar Items:
-
Starting an eBay Business For Dummies (For Dummies (Business & Personal Finance))
-
eBay Business All-in-One Desk Reference For Dummies (For Dummies (Business & Personal Finance))
-
eBay For Dummies (For Dummies (Computer/Tech))
-
eBay Listings That Sell For Dummies (For Dummies (Computer/Tech))
-
eBay Timesaving Techniques for Dummies
ASIN: 0764579061 |
Book Description
- Features ready-to-use applications-all available on the CD-ROM-that eBay sellers can plug right into their pages; more advanced users can tweak the applications to suit specific needs
- Shows you how to streamline an eBay business by leveraging programming technologies and the eBay API (application program interface)
- Explains how to connect eBay pages to the APIs of related companies (PayPal, Fed Ex, UPS, and the USPS) as well as to Microsoft Office applications such as Outlook and Excel
- Provides expert tips and tricks for implementing eBay technologies such as image handling, shipping calculators, enhanced About Me pages, and back-office tools
Download Description
* Shows you how to streamline an eBay business by leveraging programming technologies and the eBay API (application program interface) * Explains how to connect eBay pages to the APIs of related companies (PayPal, Fed Ex, UPS, and the USPS) as well as to Microsoft Office applications such as Outlook and Excel * Provides expert tips and tricks for implementing eBay technologies such as image handling, shipping calculators, enhanced About Me pages, and back-office tools
Customer Reviews:
Tries Hard to Cover Everything.......2005-03-01
A significant proportion of this book is dedicated to producing well presented listings. Easy HTML for ebay does a far better job of covering the same ground. There are also alot of quick tips that are easy to apply (and have been better covered in books such as ebay hacks).
Most of the software packages on the CD are trial versions. Nothing innovative or new is included.
The descriptions of the ebay sandbox and API are very superficial - enough to get you started but little else. The chapter on office development tells you that "serious"
experience is required and little information is availible from the ebay development site and advises the reader to concentrate on PHP - not bad advice but it takes 7 pages to get there.
Conclusion: the scope of the book is overambitious. It results in a good description of how to prepare listings, some useful tips and a superficial introduction to the ebay API.
Average customer rating:
|
Restructuring Culture: Identification of Difference and the Regulation of Change in Ex-Mining Communities (Urban and Regional Planning and Development Series)
Gary Pattison
Manufacturer: Ashgate Publishing
ProductGroup: Book
Binding: Hardcover
Economic Policy & Development
| Economics
| Business & Investing
| Subjects
| Books
General
| United States
| Americas
| History
| Subjects
| Books
Reference
| Historical Study
| History
| Subjects
| Books
General
| England
| Europe
| History
| Subjects
| Books
Social Services & Welfare
| Poverty
| Current Events
| Nonfiction
| Subjects
| Books
General
| Social Sciences
| Nonfiction
| Subjects
| Books
General
| Sociology
| Social Sciences
| Nonfiction
| Subjects
| Books
Rural
| Sociology
| Social Sciences
| Nonfiction
| Subjects
| Books
History
| Sociology
| Social Sciences
| Nonfiction
| Subjects
| Books
Culture
| Sociology
| Social Sciences
| Nonfiction
| Subjects
| Books
ASIN: 1840143304 |
Average customer rating:
|
Jim Crow Guide: The Way It Was
Stetson Kennedy
Manufacturer: Florida Atlantic University, Department of Po
ProductGroup: Book
Binding: Paperback
1950s
| 20th Century
| United States
| Americas
| History
| Subjects
| Books
General
| World
| History
| Subjects
| Books
Slavery & Emancipation
| World
| History
| Subjects
| Books
America
| Race Relations
| Sociology
| Social Sciences
| Nonfiction
| Subjects
| Books
General
| Race Relations
| Sociology
| Social Sciences
| Nonfiction
| Subjects
| Books
General
| Sociology
| Social Sciences
| Nonfiction
| Subjects
| Books
Social Groups
| Sociology
| Social Sciences
| Nonfiction
| Subjects
| Books
Discrimination & Racism
| Social Sciences
| Nonfiction
| Subjects
| Books
Human Rights
| Constitutional Law
| Law
| Subjects
| Books
Similar Items:
-
The Klan Unmasked
-
After Appomattox: How the South Won the War
ASIN: 0813009871 |
Book Description
Jim Crow Guide documents the system of legally imposed American apartheid that prevailed during what Stetson Kennedy calls "the long century from Emancipation to the Overcoming." The mock guidebook covers every area of activity where the tentacles of Jim Crow reached. From the texts of state statutes, municipal ordinances, federal regulations, and judicial rulings, Kennedy exhumes the legalistic skeleton of Jim Crow in a work of permanent value for scholars and of exceptional appeal for general readers.
Customer Reviews:
Jim Crow 101.......2003-08-27
"Jim Crow Guide: The Way It Was", is an excellent 'guide' to life in the Jim Crow South. Stetson Kennedy's book amply captures this era, when terriorism of an entire class of U.S. citizens, in the South, was the order of the day. The author's style of writing and unique presentation technique, makes this work easy reading for general readers and all students of American History from 9th grade and above.
Average customer rating:
- It wasn't supposed to be this hard.
- Impressive
- Now for the bad news
- An excellent, readable overview of vaccine research
- They themselves are the experiment
|
Shots in the Dark: The Wayward Search for an AIDS Vaccine
Jon Cohen
Manufacturer: W. W. Norton & Company
ProductGroup: Book
Binding: Paperback
General
| Science
| Subjects
| Books
AIDS & HIV
| Diseases
| Medicine
| Subjects
| Books
General
| Medicine
| Subjects
| Books
History
| Special Topics
| Medicine
| Subjects
| Books
General
| Research
| Medicine
| Subjects
| Books
Research
| Medical
| Professional & Technical
| Subjects
| Books
Similar Items:
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Viral Sex: The Nature of AIDS
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Big Shot: Passion, Politics, and the Struggle for an AIDS Vaccine
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And the Band Played On: Politics, People, and the AIDS Epidemic
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Aids Doctors: Voices from the Epidemic: An Oral History
-
Black Death: AIDS in Africa
ASIN: 0393322254 |
Book Description
As HIV continues its death march around the globe, now infecting 40 million people, an AIDS vaccine still remains an elusive goal. When scientists first proved in 1984 that HIV causes AIDS, a vaccine race quickly spun into action with high hopes that the world would soon have a means to stop this modern plague. But today the race to develop an AIDS vaccine more closely resembles a crawl. Jon Cohen, a leading AIDS reporter, tells how the forces inside and outside the world of science have hindered the AIDS vaccine search. He reveals the complicated obstacles that stymie researchers, the uncertain marketplace that confronts pharmaceutical and biotechnology companies, the haphazard political response, and the ethical dilemmas that give pause to everyone involved. He goes behind the scenes at academic labs, companies, government agencies, scientific meetings, and investment houses to document how promising leads go nowhere as scientists jump from one fashionable idea to the next. Beyond a critique of the current methods and strategies, this book also offers specific recommendations for accelerating AIDS vaccine research.
Customer Reviews:
It wasn't supposed to be this hard........2006-08-04
Jon Cohen tells the microbiological detective story in which some of the best brains in science have been pitted against the most extraordinary bug the world has ever seen. In 1984 it was discovered that HIV was the cause of AIDS. Straight away, there were confident predictions that there would be a vaccine ready for testing in just two years. Back then, just 1,292 deaths from AIDS had been reported. Now the figure is 25 million dead. By 2010 it is predicted there will be 85 million infections and 70 million deaths. And after 20 years there is still no sign of a vaccine. Despite work of dazzling complexity, the ambition of so many brilliant scientists has been constantly thwarted. Just as a vaccine seems to be working, the AIDS virus alters itself, and ten to fifteen years of work, and millions of dollars, go down the drain. These bitter disappointments are only compounded by the desperate human urgency of the work. The virus is impervious to almost everything you throw at it, says Cohen. Shots in the Dark: The Wayward Search for an AIDS Vaccine, is a story where the clock doesn't stop ticking.
Impressive.......2005-09-10
The book is nothing short of a fantastic account of the events which have shaped policy and prejudice of the AIDS anatomy and policy. At first the chapter all about Saul was wierd. Wondering where is the author leading me, and the chapter on the companies in it for PURE profit, and not creating ANYTHING worth publising. And of course you can't leave out the workings of a beaurocratic government (HA)! I had to drop the book after about 3/4 through it just because it started to write/read like a history book - which is why it gets four stars instead of five. As far as content and points of view (unbiased) it was GREAT and would recommend to anyone interested in POLICY of governments, companies, public view, and history of expirments shaping the AIDS vaccine (or should I say cure since there will never be a true "vaccine").
Now for the bad news.......2005-07-09
Reviewers of Jon Cohen's Shots in the Dark have uniformly praised his insight and investigation into the world of HIV/AIDS research. His careful accounting has exposed weaknesses of the American national biomedical research endeavor led by the National Institutes of Health (NIH).
Few if any reviewers have commented on the veracity of his conclusion. HIV/AIDS research is a political hot potato.
But one thing that should be obvious to most readers is that two decades of trying to model HIV with a different disease in a species not normally infected with the experimental disease, has been an abject, costly, and misleading failure. Cohen's response is a strident call for more, much much more, of the same.
Human immunodeficiency virus is a retrovirus that causes disease only in humans. It is a species-specific disease. Chimpanzees infected with HIV display very mild transient symptoms. Nothing regarding HIV infection in humans or in the treatment of AIDS has been a result of the use of chimpanzees. This has been acknowledged by leading primate researchers such as Dr. Thomas Insel, past director of the Yerkes National Primate Research Center at Emory University and now director of the National Institute of Mental Health.
Sooty mangabeys, an African monkey, are natural carriers of a disease called simian immunodeficiency virus (SIV). In spite of the similar name, HIV and SIV are caused by different viruses. When macaques, an Asian genus of monkey, are infected with a serially-passaged SIV, they become terminally ill. They develop chronic nosebleeds, diarrhea, and anorexia as they progress to morbidity.
This fact was discovered when the poor husbandry methods of the nation's NIH monkey labs inadvertently allowed the wide-spread infection of macaques with SIV. The disease was identified when primate researchers read about the symptoms of HIV. Always on the lookout for a new moneymaking animal model, the primate research community quickly claimed that the newly discovered disease would be a productive model of HIV.
Many hundreds of millions of dollars later, they are still asking the American taxpayer to be patient and to give them more money to kill many more monkeys.
In light of the fact that everything known about AIDS and how to treat the disease has been a direct result of human cell studies, clinical studies, and epidemiological research, it is difficult to understand why Cohen still stands with the monkey researchers and urges more money be shoveled into this black hole of proven failure. The only answer I can imagine is that he is just enamored with anything that looks like science.
Readers unfamiliar with the history of the failure of the monkey and chimpanzee models are likely to come away from Shots in the Dark with a very wrong-headed idea of how we ought to be spending our finite resources to stop this pandemic. To this extent, the book is dangerous and likely to have negative consequences if decision makers take Cohen's recommendations to heart.
In spite of this, as a historical accounting, I found the book to worthwhile.
An excellent, readable overview of vaccine research.......2002-12-19
Jon Cohen is probably the most knowledgable journalist on the topic of HIV vaccines and has been following developments in this area for over a decade. He's had unparalleled access to people working in the field and it shows in this well organized history of the search for an HIV vaccine. I used to work in this area of research and, although there are issues where I have quibbled with the author, I can think of no better introduction to the field and the key issues that have shaped it. Cohen has been uniquely able to maintain the trust and respect of key people working in the field, while also raising important social and scientific issues. The result is a thoughtful, relatively thorough chronology that is also readable and concise. At a more personal level, the book brought back many forgotten controversies and issues that formed the background for almost a decade of my own work. The writing is that vivid, while also maintaining a high standard of scientific journalism.
They themselves are the experiment.......2001-07-10
Buy this book, read it, and pass it on to a friend. In short, make it infections, as it is one of the best hopes for `enlightened' men to capture the future.
This is a massive journalistic endeavor for a single man to mount, set against the hurdles of the decidedly clubby world of big-money medicine and ten-plus years of the Byzantine complexities of many different scientific disciplines, not one. Its factual, story-to-tell approach, is a breath of fresh air in a miasma of empty government panel reports, obtuse scientific ramblings, sensationalist hardcopy, and necessarily overstated activist rancor. For those who take time with it, it works its way, not "into your face", but slowly into your heart.
For the less passionate, however, it is not clear, that this book, stoutly rendered by Cohen and W.W.Norton, carries its burden of proof, in all cases. Where are the numbers? We read that vaccine research persistently remained at 10% of the overall NAIAD budget, but, W.W., a data table would have been nice. The same with the grant evaluation-success rates and total project funding(s), and other small things here and there. But these points hardly sacrifice the whole. The broader picture and point to be made is overwhelmingly clear: Physician, help thyself! Alternatively, one might call it, "When bad things happen to really, really smart people."
This realization builds from page to page with almost every conflict and with almost every story of pursuit recounted. **The "endless frontier" of medicine-man-directed-science has not been expansive enough to include the basic, fundamental lessons of process science, risk bearing and decision making under uncertainty, strategic planning, and public relations.** It is no accident that Jonas Salk's last recounted wish is for "better ways", and the attentive reader will find similar hints or cries for help from other scientists as well.
Since 1981, it is a time for *war*, man against microbe. These scientists seem to miss the lessons of the *harsh*, *daily* reality that THEY AND THEIR ETHOS *ARE* THE EXPERIMENT!
This is true, notwithstanding, of course, of the great "Nobel prize experiment", that perniciously hangs like a collaboration-distracting "mirror, mirror" amid the lab-rats. At other times, the profession also seems oddly self-aware, as the paucity of those interested in putting themselves in harm's way of such a dashing "experiment" is laid bare, for example, while the directorship for the new NIH Vaccine Center goes unwanted.
Now, in 2001, the field seems blood red and who will say which fault belongs to whom? Who could fault the NIH, who, after all, have only the power to subsidize? Who could fault the politicians, who thought the scientists had it "under control (at least contained, ahem!) and adequately funded"? Who could continue to fault the system, when incremental changes have been made? Finally, what Prince will come at the end to say, "And I, for winking at your discords too, have lost a brace of kinsman?"
Yet the notion that Cohen suggests, that, after twenty years, "the world is watching", does nothing but turn up the heat on a pot with the same ingredients. One cannot look into Dr. Fauci's or Dr. Baltimore's eyes, for instance, and think that these researchers, these captains, are utterly bankrupt, immoral egoists or that they have deaf ears, deaf ears to the 60 million that may die one of the most miserable deaths possible, surrender (insofar as the human mind could even comprehend the magnitude of such a loss).
To be fair - and hopeful -, the medical profession, has let itself open to study and critique, far, far more than others. Yet, more chanticleer cries will repeat the past, for what may be needed now are truly better ways, diversity of thought, competence in management, and sufficiency in funding - the hard work, not the low-hanging fruit; settling in for the long-run; in short, the next 20 years.
The Buddhists believe that a single man can change the world. This reviewer hopes that others who read this book also have vigor enough to take a trumpet to Washington, not to wake anyone up, but like Joseph on the way to Jericho, truly a March of D-times.
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Lake sediment creates new park.(NRPA in Action): An article from: Parks & Recreation
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Release Date: 2005-06-01 |
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This digital document is an article from Parks & Recreation, published by National Recreation and Park Association on September 1, 2004. The length of the article is 355 words. The page length shown above is based on a typical 300-word page. The article is delivered in HTML format and is available in your Amazon.com Digital Locker immediately after purchase. You can view it with any web browser.
Citation Details
Title: Lake sediment creates new park.(NRPA in Action)
Publication:
Parks & Recreation (Magazine/Journal)
Date: September 1, 2004
Publisher: National Recreation and Park Association
Volume: 39
Issue: 9
Page: 142(1)
Distributed by Thomson Gale
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